[Signman]

Try replacing you O2 sensor they do go bad due to the leaded fuel. Also location should matter at low RPM but upstairs should not be a big influence unless you have a header leak, make sure there are no leaks at the flanges.
Raising fuel pressure should richen across the map but the ECU does not know it, it's best to add fuel by editing the table.
The internal data logger works pretty well for tuning when you indicate an area on the log open tables will show which cells are being used. Tables should have there dashboard closed for this to work. use percentage to make changes: the difference between actual and target O2 in percentage is added or subtracted from number in cell.

MOST Important: Always save your base file where you will not delete it.
Always save your tune with a unique file name when making changes (facility;date;run#). Much easier to go back where you were if the change did not work get lost which is easy.

You should be logging RPM, Fuel, Timing, O2, Voltage at least.
Cells are divided in RPM increment usually 500, in the data log select RPM range in high gear for a suspect cell. This will then give you averages on the dashboard below, have the fuel table open with its' dashboard off, cell being used in fuel map will be indicated. Make changes then make another run.